Ad-RAB:
Anti Rabies Serum (Premi-RAB) contains purified enzyme refined equine immunoglobulin fraction – Low Fc content minimizes possibility of anaphylactic reactions.
INDICATIONS:
Mainly administered for passive immunity to the patients being bitten and scratched by rabies or other animals carrying rabies virus.
COMPOSITION:
(Enzyme refined equine immunoglobulins) – Liquid.
Each ml of Rabies Anti Serum contains not less than 300 I.U.
Phenol (Preservative) - NMT 0.25% w/v.
Glycine I.P. - Stabilizer.
Sodium Chloride I.P. - Excipient.
DOSAGE:
Rabies Antiserum should be given immediately after the bite preferably within 24 hours of animal bite to get maximum benefit. It can be administered up to 7 days after administration of first dose of vaccine. Recommended dose is 40 IU/kg body weight up to a maximum of 3000 I.U. Children and adults to receive the same dose of 40 IU/kg. of body weight. As much of the calculated dose as anatomically feasible should be infiltrated into and around the wounds. The rest of the dose should be given intramuscularly as a single dose (in the gluteal region) followed by a complete course of vaccine, but in a different part of the body (upper part of arms, deltoid region). If calculated dose is insufficient to infiltrate all wounds, It can be diluted in Normal saline 2-3 folds. Immunocompromised / immunosupressed individuals even with Category II exposures need Rabies Antiserum.
STORAGE:
It should be stored at +2˚ to + 8˚ C. Do not freeze and keep protected from heat.
SHELF LIFE:
Two years.